6 Napier Rd, #02-10 Gleneagles Medical Centre, Singapore 258499 +65 8849 0677 baselneurosurgery@bone.com.sg
Book appointmentBook

Home  /  Conditions  /  Gout

Gout

Sudden, severe joint pain caused by uric acid crystals — most often at the base of the big toe. An attack settles within days; keeping uric acid low is what stops the next one.

A man describing his symptoms to a doctor who is taking notes on a tablet.
What it is
Arthritis caused by uric acid crystals forming in and around a joint.
Commonest joint
The base of the big toe, then the foot, ankle and knee. The hands and wrists can be affected too, usually later on.
The long-term aim
Keeping uric acid low enough that crystals dissolve and stop forming.

What is gout?

Uric acid is a normal waste product, made when the body breaks down substances called purines. It usually dissolves in the blood and leaves through the kidneys. When there is more than the body can clear, it can form sharp, needle-like crystals in and around joints.

The immune system reacts to those crystals with sudden, intense inflammation — a gout attack, or flare. Between attacks the joint can feel completely normal, but the crystals are still there. Over years, repeated attacks can damage the joint, and crystals can collect under the skin as lumps called tophi.

High uric acid does not always mean gout. Many people have raised uric acid in a blood test and never have an attack. Treatment is decided by attacks, tophi and joint damage, not by a number on its own.

Gout, infection or pseudogout? Three causes of a hot, swollen joint

A red, hot, swollen joint can have more than one cause, and one of them is an emergency. They can look alike, so the joint fluid is often what settles it.

 GoutJoint infectionPseudogout
Typical jointBig toe, foot, ankle, knee; fingers, wrist and elbow in long-standing goutKnee or hip most often, but any jointKnee, wrist
How it startsOften overnight, peaking within a dayOver hours to days, and keeps getting worseOver a day or two
FeverSometimes, mildCommon, with feeling generally unwellSometimes
More likely inMen from middle age, women after menopausePeople with diabetes, a joint replacement or weakened immunityAdults over 60
Joint fluid showsUric acid crystalsBacteriaCalcium crystals

A joint infection can destroy a joint within days, and gout and infection can occur together. A hot, swollen joint with fever needs to be seen the same day. A bunion affects the same big toe joint but causes a bony bump and aching, not sudden hot swelling.

Gout symptoms

  • Sudden, severe pain in one joint, often starting at night and worst within the first day
  • Redness, heat and swelling; the skin over the joint may look shiny
  • Extreme tenderness — even the weight of a bedsheet can hurt
  • The attack easing over one to two weeks, even without treatment
  • With long-standing gout: more frequent attacks, more joints affected, and firm lumps (tophi) on the toes, fingers, elbows or ears

What causes it

Too much uric acid

  • Most often, the kidneys clearing too little
  • Less often, the body making too much
  • Family history

Diet and drink

  • Beer and spirits
  • Sugary drinks sweetened with fructose
  • Red meat, organ meats and some seafood

Health and medicines

  • High blood pressure, diabetes, kidney disease, excess weight
  • Some medicines, including water tablets (diuretics)

Common triggers for an attack

  • A heavy drinking session or large meal
  • Dehydration, illness or surgery
  • Starting, stopping or changing uric-acid-lowering medicine

Signs that need seeing today

  • A hot, swollen joint with fever, chills or feeling generally unwell
  • A joint replacement that becomes hot, swollen or very painful
  • A first-ever attack of a hot, swollen joint, when the cause is not yet known
  • Pain and swelling that keeps worsening after two to three days

Call us on +65 8849 0677. We will see you the same day where we can.

If we are closed, go to an emergency department — we are shut on Sundays and after 1pm on Saturdays. A possible joint infection should not wait.

Call +65 8849 0677

How gout is diagnosed

  • History and examination — which joint, how quickly the attack came on, previous attacks, medicines and alcohol
  • Joint fluid test — a small sample drawn from the joint with a needle and checked for crystals. The most reliable way to confirm gout, and to rule out infection
  • Blood tests — uric acid, kidney function, and signs of inflammation
  • Ultrasound — can show crystal deposits on the joint surface
  • Dual-energy CT — can show urate crystals directly, where the diagnosis is uncertain
  • X-ray — mainly for joint damage from long-standing gout

Uric acid can read normal during an attack. Levels often fall while a joint is inflamed, so a normal result does not rule gout out. The test is usually repeated a few weeks after the attack settles.

Gout treatment

Treatment has two separate jobs: settling the attack you have now, and preventing the next one.

Treating the attack

Anti-inflammatory tablets, colchicine, or a steroid — as tablets or an injection into the joint. Treatment works best started early. Rest the joint, raise it, and use a cold pack wrapped in a cloth.

Lifestyle changes

Cutting down on beer, spirits and sugary drinks, eating less red meat and organ meat, keeping well hydrated, and losing excess weight all help. Some medicines that raise uric acid may be reviewed. For people with repeated attacks, diet alone is rarely enough.

Uric-acid-lowering medicine

Recommended for repeated attacks, tophi, joint damage or kidney stones. Allopurinol is the usual first choice, with febuxostat an alternative. The dose starts low and is raised step by step, with blood tests, until uric acid is below target — usually under 360 µmol/L, and lower where there are tophi.

  • Attacks can increase at first, as crystals start to dissolve. A low dose of colchicine or an anti-inflammatory is often taken for the first few months to prevent this
  • Keep taking it during an attack; stopping and starting makes attacks more likely
  • It is usually long-term, with regular blood tests
  • For people of Han Chinese, Korean or Thai descent, a genetic blood test (HLA-B*5801) may be recommended before allopurinol, because of a rare but serious skin reaction

Surgery

Rarely needed. Considered for large tophi that cause pain, skin breakdown or infection, or for a joint that gout has badly damaged.

Why see us about it

  • The right diagnosis first. Joint infection and pseudogout are ruled out, not assumed away.
  • Both jobs, not just one. The attack is treated, and a plan is made to prevent the next.
  • The joint itself. Where gout has damaged a joint in the foot, ankle or knee, orthopaedic assessment is in the same clinic.

Common questions

What should I do during a gout attack?

Rest and raise the joint, apply a wrapped cold pack, drink plenty of water, and start the treatment your doctor has advised as early as possible. If you already take uric-acid-lowering medicine, keep taking it. A hot joint with fever needs to be seen the same day.

My uric acid was normal. Can it still be gout?

Yes. Uric acid often falls during an attack, so a normal result does not rule gout out. A joint fluid test, or a repeat blood test a few weeks later, gives a clearer answer.

Can diet alone control gout?

It helps, but for most people with repeated attacks it is not enough on its own. Diet has a modest effect on uric acid; medicine is usually needed to bring it below target.

Will I need medicine for life?

Uric-acid-lowering medicine is usually long-term. Stopping it lets uric acid rise again and crystals re-form, and attacks often return.

Is it gout or a bunion?

Both affect the base of the big toe. A bunion is a bony bump with aching that builds slowly. Gout comes on suddenly, with a red, hot, very tender joint.

Do I need a referral to see a gout doctor?

No. Bring any blood test results, a list of your medicines, and dates of previous attacks if you have them.

Related conditions

Foot pain · Bunions · Ankle pain · Knee pain · Knee osteoarthritis · Hand arthritis

Book a consultation

If the joint is hot and swollen now, call rather than book online. Seeing it during an attack helps confirm the cause.

Book an appointment Call +65 8849 0677
Address
6 Napier Road, #02-10
Gleneagles Medical Centre
Singapore 258499
Phone
+65 8849 0677
Mon–Fri
9:00 am – 5:30 pm
Saturday
9:00 am – 1:00 pm
Book an appointment Choose a doctor & time